3D printing porous implants bakeng sa phekolo ea bokooa ba masapo ke katleho e ncha lefapheng la boenjiniere ba lisele. U sebelisa theknoloji ea khatiso ea 3D, moralo o nepahetseng oa micropore o ka etsoa ka mekhahlelo ea 'mele e kang boholo ba pore, porosity, pore pore le topography ea holim'a lintho tse kenngoeng. Molemo ona ke ho le thata ho bapisa le scaffolds tsa setso lesapo implant, kahoo ho ka hlahiswa Personalized implants le ho feta loketseng biocompatibility le thepa ea mechine e ka finyella ka botlalo litlhoko tsa bakuli.
Hobaneng u khetha alloy ea titanium
Titanium le li-alloys tsa titanium ke mofuta oa lisebelisoa tsa tšepe tse ileng tsa qala ho hola butle-butle bohareng ba lekholo la bo20 la lilemo. E na le litšobotsi tsa letsoalo le tlase, matla a khethehileng a phahameng, ho hanyetsa kutu e ntle, le biocompatibility e ntle. E sebelisoa haholo libakeng tsa sefofane, petrochemical le bongaka le bophelo bo botle.
Mokhahlelo oa pele
Mabapi le ho sebelisoa ha titanium linthong tse kenngoeng tsa bongaka, khale koana ka 1940, litsebi li ile tsa tlaleha ho se be teng pakeng tsa ho kenngoa ha titanium le li-femurs tsa mouse. Ka 1951, litsebi tse ling li ile tsa tiisa hape hore titanium e hloekileng e na le biocompatibility e betere ho feta lisebelisoa tse ling tsa setso. Leha ho le joalo, ka lebaka la litšenyehelo tse phahameng tsa tlhahiso ea li-alloys tsa titanium le 'maraka o holileng oa tšepe e sa hloekang ka li-implants, ts'ebeliso le nts'etsopele ea li-alloys tsa titanium lefapheng la bongaka e bile butle.
Ntlha ea bobeli
Ho tloha lilemong tsa bo-1960, titanium e hloekileng e 'nile ea sebelisoa lipatlisisong tsa molomo tsa bongaka e le ho kenngoa ha motho. Ka nts'etsopele ea li-alloys tsa Ti-6Al-4V tse nang le ts'ebetso e ntle haholo, li-alloys tsa titanium li se li qalile ho sebelisoa haholo 'marakeng oa implant ea bongaka.
Bothata boo re tobaneng le bona
Le hoja modulus ea elastic ea Ti-6Al-4V e ka bang 114GPa feela, e ka tlaase ho feta lisebelisoa tse ling tsa likokoana-hloko tse kang tšepe e sa hloekang le cobalt-chromium alloy, e ntse e le e 'ngoe e phahameng ho feta lesapo la cortical ea motho (15-25GPa) le lesapo la ho hlakola (0.05-3GPa) Boholo. Phapang e kholo joalo e tla etsa hore seo ho thoeng ke "stress shielding" se etsahale, e leng se tla etsa hore ho be le lesapo le pota-potileng ho kenngoa ha nako e telele, esita le ho etsa hore ho kenngoa ha eona ho fokotsehe, ho fokotsa katleho ea ho kenngoa ha masapo.
Phello ea "stress shielding" e bua ka modulus ea elastic ea bioloji e kentsoeng (> 100GPa) le modulus ea elastic ea lesapo la receptor.
Ka nako e ts'oanang, Al, V le likarolo tse ling tse teng sebopehong li na le chefo e itseng ea likokoana-hloko. Tšebeliso ea nako e telele 'meleng oa motho e tla baka maqeba a lisele ho pota-pota le ho hlahisa matšoao a kang encephalopathy le phokolo ea mali. Ha e loketse ho sebelisoa nako e telele 'meleng oa motho. .
Tharollo Chefo ea likokoana-hloko
Lilemong tsa morao tjena, bakeng sa li-alloys tsa titanium tsa likokoana-hloko, bafuputsi ba thehile li-alloys tsa Gum tse nang le li-alloys tsa Ti-Nb-Ta-Zr le TLM tse nang le Ti-Nb-Zr-Mo-Sn ho pota-pota litšobotsi tsa non-toxicity le low elastic modulus. Le alloy ea Ti2448 e nang le Ti-Nb-Zr-Sn, joalo-joalo, li-alloys tsena kaofela li sebelisa Nb, Zr, Mo le likarolo tse ling tse nang le biocompatibility e ntle. Liphetho tsa liteko li bontša hore ts'ebetso ea likokoana-hloko ea li-alloys tse joalo tsa titanium tse kang ho phahamisa lesapo le ho matlafatsa maikutlo li molemo ho feta Ti-6Al-4V le Ti-6Al-7Nb tse sebelisoang li-implants tsa setso.
Ho sireletsa khatello ea maikutlo
Lintlha tsa lipatlisiso li bonts'a hore nts'etsopele ea lisebelisoa tsa porous e ka fokotsa ka nepo modulus ea elastic, ea fana ka sebaka sa 'mele bakeng sa ho kenella ha masapo, le ho matlafatsa ho tiisa masapo. Bakeng sa lisebelisoa tsa porous tse kentsoeng lesapo, litsebi tse ling li tlalehile hore porosity e lokela ho laoloa pakeng tsa 65% le 80%. Bakeng sa lisebelisoa tsa ho kenya tse nang le porosity e feteletseng, porosity e tla fokotsa haholo matla a khatello le mokhathala oa thepa, e ke keng ea finyella litlhoko tse tloaelehileng tsa tšebeliso ea thepa; ha thepa ea porous e ka tlaase ho boleng bona e na le matla a phahameng, Ama lesapo la masapo hore le hōle ka har'a thepa le ho fokotsa matla a ho kopanya pakeng tsa ho kenngoa le thepa.
Papiso ea mokhoa oa setso oa khatiso oa VS3D
E le ho finyella litlhoko tsa moralo oa porosity ea lisebelisoa tse boletsoeng ka holimo, mekhoa ea setso ea ho itokisa ea lisebelisoa tsa porous titanium alloy haholo-holo e kenyelletsa: mokhoa oa metallurgy oa phofo, mokhoa oa slurry le mokhoa oa fiber sintering.
Leha ho le joalo, lisebelisoa tsa porous tse hlahisoang ke mekhoa e joalo ka kakaretso li na le li-diameter tse nyenyane tsa pore, kabo e sa lekaneng ea pore, e tlaase ka ho fetisisa, kapa palo e kholo ea li-micropores mohahong oa lerako la pore, e leng se thibelang tsoelo-pele ea bona e tsoelang pele tšimong ea biomaterials. Lilemong tsa morao tjena, ka ho kenyelletsoa ha theknoloji ea "3D printing", ka lebaka la litšobotsi tsa eona tsa ts'ebetso, melemo ea ho sebelisa khatiso ea 3D ho etsa lisebelisoa tsa porous e se e bonahala haholoanyane.
Nakong e tlang, ka tharollo ea porous material porosity le pore size, elastic modulus, biological toxicity le litaba tse ling, hammoho le ho kopanngoa le katleho ea lithuto tse fapa-fapaneng ho kenyeletsa mahlale a thepa, theknoloji ea stem cell, joalo-joalo, 3D khatiso ea titanium alloy substitutes e tla fetoha mofuta oa botho.
Khatiso e hatisitsoeng ea laser titanium alloy
References:
"Tensile thepa ea 3D e hatisitsoeng ea titanium alloy trabecular bone porous structure"
"Thuto ea Boiteko ea Liphoofolo ka Phello ea 3D Printing Porous Titanium Alloy Scaffold Pore Structure on Bone Ingrowth Effect"
"Tsoelopele ea Lipatlisiso ea 3D Printing Medical Titanium Alloys"
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